This review article examines the current and potential applications of therapeutic peptides in orthopaedic medicine, including peptides such as BPC-157, discussing their mechanisms of action, clinical uses, and the obstacles to their development and implementation in orthopedic practice (Evidence level: Review). The article identifies key challenges in peptide therapeutics, such as stability, delivery mechanisms, and regulatory pathways, while also outlining future directions for research and clinical translation in orthopedic conditions. This represents a synthesis of existing literature rather than original research data from human clinical trials or animal studies.
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