This study found that older livers are more prone to damage after transplant surgery due to increased inflammation from immune cells called macrophages. When researchers gave NMN supplements to aged mice, it restored cellular energy levels and reduced this harmful inflammation in the liver. The NMN worked by activating a protein called Sirt1 that helps control inflammatory responses. This suggests NMN could help protect older organs during surgical procedures.
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NMN supplementation can reduce harmful inflammation in aging tissues by restoring cellular energy and activating protective anti-inflammatory pathways.
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