This review article examines the copper peptide GHK (glycine-histidine-lysine) and its proposed mechanisms for counteracting age-related biological decline, including potential effects on collagen synthesis, wound healing, and cellular signaling pathways. The authors synthesize existing evidence from multiple research domains to discuss GHK’s theoretical anti-aging potential, though the review does not present new primary data. **Evidence level: Review article** (synthesis of existing literature rather than original human clinical, animal, or in vitro research).