This study looked at patients who developed methemoglobinemia, a serious blood condition where oxygen transport is impaired, after exposure to certain chemicals and drugs over 10 years in Thailand. The research focused on identifying what caused the condition, how patients presented clinically, and what happened to them. This was a safety study examining harmful effects rather than therapeutic benefits of methylene blue.
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Methylene blue is the primary rescue agent in acquired methemoglobinemia; knowing causative agents aids early clinical recognition.