This animal model study examined corneal ulcer healing mechanisms by proposing an integrated conceptual framework linking corneal ulcer healing, corneal neovascularization, and intraocular pressure changes, with comparison to avascular tendon healing processes. The research evaluated the pentadecapeptide BPC 157 as a potential therapeutic agent across these interconnected corneal pathology domains. The study presents a theoretical model for understanding corneal wound healing complications and proposes criteria for evaluating therapeutic interventions in corneal disease, though findings are based on animal model evidence.