This review article examines injectable peptide therapies, including BPC-157, relevant to orthopaedic and sports medicine practice, synthesizing existing evidence on mechanisms of action and clinical applications in musculoskeletal conditions. The review provides an overview of peptide-based therapeutic options and their potential role in orthopaedic treatment paradigms based on current literature. The evidence level is review article (synthesis of existing literature rather than original human clinical trials or animal model data).