This review article examines research on Stable Gastric Pentadecapeptide BPC 157 and its potential effects on intestinal anastomoses (surgical connections between bowel segments) based primarily on rat studies. The reviewed evidence suggests BPC 157 may influence intestinal healing processes, vascular responses, and tissue repair mechanisms at the anastomotic site in animal models. **Evidence level: Animal model and in vitro studies** with supporting mechanistic research, though the review synthesizes preclinical findings rather than presenting new clinical trial data in humans.