Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults.

This human clinical study examined CJC-1295, a long-acting GH-releasing hormone analog, and found that it stimulated prolonged secretion of growth hormone and insulin-like growth factor I in healthy adult subjects. The extended duration of hormone elevation distinguishes this compound from shorter-acting GH-releasing hormone preparations. This evidence comes from direct human clinical investigation.