This review article discusses BPC 157, a synthetic peptide, and its proposed mechanisms of action related to angiogenesis and nitric oxide regulation, responding to previous literature on the peptide’s multifunctional properties and potential medical applications. The authors address how BPC 157 may modulate the balance between protective and damaging actions of nitric oxide while promoting blood vessel formation. The evidence level is a review of existing literature rather than new primary research (review article).