Researchers investigated exosome-based nanoparticles loaded with both curcumin and methylene blue as a dual drug delivery system for Alzheimer’s disease in an animal model, evaluating effects on cognitive function and underlying mechanisms. The study found that this exosome delivery approach enhanced cognitive outcomes compared to individual drugs or unloaded exosomes, with mechanistic analysis suggesting improvements in oxidative stress reduction and neuroinflammation. **Evidence level: Animal model**